4 Furthermore, colloidal oatmeal treatment is effective in restoring the skin barrier in patients with disrupted skin barrier.Ĭolloidal oatmeal is effective as an adjunct therapy in AD patients of all age groups, improving measures of disease severity such as Investigator’s Global Assessment (IGA), Eczema Area and Severity Index (EASI), pruritus, xerosis, and quality of life. These improvements were significant two weeks after cessation of the oatmeal body cream (P=.014 P=.037 P=.003 respectively). Oatmeal-containing body cream was shown to significantly improve skin hydration, reduce skin desquamation, and reduce the surface area of dead epithelial cells compared to a control. Symptoms associated with AD, such as pruritus, skin irritation, and increased skin sensitivity, can be managed well with colloidal oatmeal. Proteins in colloidal oatmeal are very effective pH buffers that can counteract elevated skin pH and improve appropriate stratum corneum integrity, barrier function, and antimicrobial activity. AD patients, in particular, have an elevated skin pH due to disruption of the skin’s acid mantle, a slightly acidic protective film on the surface of the skin. 2 Furthermore, topical application of avenanthramides reduces inflammation and scratching in murine models. 1 Phenolic avenanthramides are thought to inhibit tumor necrosis factor-alpha induced NF-kB luciferase activity and decrease the release of interleukin-8, an inflammatory cytokine involved in neutrophil chemotaxis. Phenolic avenanthramides, though a minor component of colloidal oatmeal, are responsible for the anti-inflammatory properties of colloidal oatmeal use. Other beneficial ingredients in colloidal oatmeal are saponins, vitamins, flavonoids, and avenanthramides, some of which have antioxidant properties. With its high concentration of starches and beta-glucan, colloidal oatmeal is water-attracting and helps the skin retain water. Colloidal oatmeal has hydrating, anti-pruritic, and anti-inflammatory properties that substantiate its benefit in treating AD symptoms. doi:10.1080/ 2003, the FDA approved colloidal oatmeal as an effective skin-protectant drug for alleviating discomfort or dryness associated with various skin conditions. A 1% colloidal oatmeal OTC cream is clinically effective for the management of mild to moderate atopic dermatitis in Black or African American children. Lisante TA, Kizoulis M, Nuñez C, Hartman CL.Kenvue unveils efficacy of colloidal oatmeal in managing atopic dermatitis in Black children and shares new Neutrogena product innovations at Science of Skincare Summit.In her session, Lisante will also review the use of colloidal oatmeal in other products for strengthening the skin’s moisture barrier, soothing irritated skin, and helping to support the microbiome. Both groups showed improvement in pruritis, skin appearance, dryness/flakiness, and moisturization. In the colloidal oatmeal cream group, 100% of patients or participants reported that the cream was appropriate for use on children, and 88% said they would use the cream daily rather than occasionally. Interestingly, the diverse population included in this study provided a new opportunity to conduct a sub analysis among the group of Black subjects, who we know are more effected by eczema, to help advance community health and solve for public health challenges.” 1 “A previously published randomized study, conducted in children with atopic dermatitis, also known as eczema, the most common chronic inflammatory skin disease, had already established the safety and efficacy of an OTC 1% colloidal oatmeal cream versus a ceramide-based prescription barrier cream in relieving eczema symptoms in children with mild to moderate eczema. “When products are not tested in a diverse population, there is a reluctance to accept them as solutions,” Lisante said in a press release. In The Power of Oat for Sensitive Skin session on September 23 at 2pm CDT, lead author Tonianne Lisante, Kenvue scientific engagement manager, will detail the findings of the peer-reviewed study that was published in the Journal of Dermatological Treatment highlighting 1% colloidal oatmeal cream used at least twice daily for treating atopic dermatitis in Black children. The company will also be sharing other industry-advancing science, including solutions in cleansing and hydration from Neutrogena. Kenvue reported the findings at the Science of Skincare Summit in Austin, Texas.
0 Comments
Leave a Reply. |
AuthorWrite something about yourself. No need to be fancy, just an overview. ArchivesCategories |